Recent advances in cardiovascular research: systems biology

Recent advances in endothelin research on cardiovascular and endocrine systems.

Recent advances in ET research on the cardiovascular and endocrine systems were reviewed. Considering the potent vasculotropic actions, strategically advantageous localization, and recent findings with the specific receptor antagonist, ET is potentially involved in the regulation of hemodynamic homeostasis and in the pathogenesis of essential and secondary hypertension. The mitogenic action on ...

Recent advances in cohesin biology

Sister chromatids are tethered together from the time they are formed in S-phase until they separate at anaphase. A protein complex called cohesin is responsible for holding the sister chromatids together and serves important roles in chromosome condensation, gene regulation, and the repair of DNA damage. Cohesin contains an open central pore and becomes topologically engaged with its DNA subst...

A review on the recent advances in the biology and aquaculture technology of Holothuria scabra

The highly valued sea cucumber Holothuria scabra is currently listed as endangered (EN) species in the IUCN Red List due to overfishing in most of its native locations, spurring the development of H. scabra aquaculture to ensure sustainability of the industry and species in the wild. This review presents a summary on the biology of Holothuria scabra and recent advancements of its aquaculture te...

Recent advances in melanoma biology.

The incidence and mortality rates of melanoma have increased at annual rates of 2%-3% for the last 30 years. Disseminated disease is largely refractory to cytotoxic chemotherapy and is almost universally fatal. Several recent advances in melanoma biology offer new strategies for potentially treating this aggressive malignancy. This review focuses on three significant advances involving tumor in...

Systemic Approaches in Bioinformatics and Computational Systems Biology : Recent Advances